Drug Standards
Apexbio Technology LLC Enzastaurin (LY317615) 170364-57-5 100mg
Enzastaurin (LY317615 CAS 170364-57-5) is an orally bioavailable ATP-competitive inhibitor selective for protein kinase C beta (PKC ) a member of the serine-threonine kinase family implicated in tumor growth and progression By inhibiting PKC (IC50 6 nM) enzastaurin decreases phosphorylation and signaling of downstream effectors including ribosomal protein S6 GSK3 and AKT In cellular assays enzastaurin reduces proliferation and induces apoptosis across diverse tumor types (e g colon cancer HCT-116 glioblastoma U87MG) In vivo studies demonstrate antitumor efficacy in xenograft models highlighting its utility for oncology research
Medchemexpress LLC Lenalidomide-5-Br | 1010100-26-1 | MFCD32263142 | 99.9% | 323.15 | C13H11BrN2O3 | 50 G
Lenalidomide-5-Br is a lenalidomide-derived cereblon (CRBN) ligand used to recruit the CRBN E3 ligase; it is supplied as a solid and is intended for use as a building block in PROTAC synthesis and other targeted protein degradation workflows.
- Chemical formula C13H11BrN2O3.
- Molecular weight 323.15 g/mol.
- Cas number 1010100-26-1.
- Purity 99.87% (reported by manufacturer).
- Solubility DMSO 12.5 mg/mL; water <0.1 mg/mL (insoluble).
- Recommended storage powder -20°C (3 years) or 4°C (2 years); in solution -80°C (6 months) or -20°C (1 month).
- Typical applications building block for PROTACs and CRBN recruitment in targeted protein degradation studies.
Sigma Aldrich Fine Chemicals Biosciences Cefmetazole United States Pharmacopeia (USP) Reference Standard | 56796-20-4 | 200MG
Cefmetazole United States Pharmacopeia (USP) Reference Standard | Mol Wt: 471.53 | 56796-20-4 | 200MG
Sigma Aldrich Fine Chemicals Biosciences Sulbactam United States Pharmacopeia (USP) Reference Standard | 68373-14-8 | MFCD00867005 | 250MG
Sulbactam United States Pharmacopeia (USP) Reference Standard | Mol Wt: 233.24 | 68373-14-8 | MFCD00867005 | 250MG
Selleck Chemical LLC Haloperidol 5mg 52-86-8
Haloperidol (Haldol) is an antipsychotic and butyrophenone. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical R-FlurbIprofen 500mg
A COX-inactive enantiomer of flurbiprofen; inhibits γ-secretase activity in vitro; reduces formation of Aβ42 and improves axonal transport in young Aβ-plaque free mice in the Tg2576 transgenic model of Alzheimer's disease; inhibits NF-kB activation and DNA binding as well as AP-1 DNA binding in RAW 264.7 macrophages; reduces paw edema in a rat model of zymosan-induced inflammation at 1, 3, and 9 mg/kg; suppresses prostate tumor cell growth in vitro and reduces tumor growth and metastasis in multiple mouse models of intestinal neoplasia
Cayman Chemical HexnoIc AcId-d11 1g
An internal standard for the quantification of hexanoic acid by GC- or LC-MS
Chem-Impex International, Inc. Amphotericin B | 1397-89-3 | MFCD00877763 | 1G
Amphotericin B, 1397-89-3, MFCD00877763, 1G
Medchemexpress LLC Amoxicillin piperazine-2,5-dione | 94659-47-9 | 25mg
Amoxicillin Impurity 7 is an impurity of Amoxicillin (HY-B0467A)
Medchemexpress LLC Tenofovir Disoproxil fumarate | 202138-50-9 | 99.5% | 635.51 | 50 MG
Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. It is for research use only.
- Used to treat HIV and chronic Hepatitis B
- Functions as a nucleotide reverse transcriptase inhibitor
- Shows cytotoxic effects on HK-2 cells with IC50 values of 9.21 and 2.77 μM at 48 and 72 hours
- Diminishes ATP levels and increases oxidative stress in HK-2 cells
- Induces apoptosis in HK-2 cells via mitochondrial damage
- Inhibits replication of R5-tropic HIV-1BaL and X4-tropic HIV-1IIIb in activated PBMCs
- Significantly reduces HIV transmission in BLT mice
- Induces dose-dependent decline in serum viremia in woodchucks chronically infected with WHV
- Demonstrated as safe and effective in the woodchuck model of chronic HBV infection
Medchemexpress LLC Methyl linolenate | 301-00-8 | 99.5% | 292.46 | 5 G
Methyl linolenate is a polyunsaturated fatty acid (PUFA) that exhibits anti-melanogenesis activity with an IC50 of 60 μM. It is utilized for research into the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids. In vitro, Methyl linolenate (50, 100 μM, 48 h) significantly down-regulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins in B16F10 cells.
- Polyunsaturated fatty acid (PUFA)
- Exhibits anti-melanogenesis activity
- Supports research on oxidation/peroxidation prevention
- Down-regulates MITF and tyrosinase-related proteins
- Purity of 99.46%
- Molecular formula C19H32O2
- Appearance as a colorless to light yellow liquid
Selleck Chemical LLC Cladribine S1199-1g
Cladribine is an adenosine deaminase inhibitor for U266 RPMI8226 and MM1 S cells with IC50 of approximately 2 43 M 0 75 M and 0 18 M respectively
Medchemexpress LLC Mogroside IIe | 88901-38-6 | 1 ML
Mogroside IIe is a nonsugar sweetener known for its sweetness, which surpasses that of sucrose. This compound is recognized for its antioxidant, antidiabetic, and anticancer properties.
- Nonsugar sweetener
- Sweeter than sucrose
- Exhibits antioxidant activity
- Exhibits antidiabetic activity
- Exhibits anticancer activity
Apexbio Technology LLC Fluvoxamine maleate 61718-82-9 10mM (in 1mL DMSO)
Fluvoxamine maleate (CAS 61718-82-9) is a selective serotonin reuptake inhibitor that acts by inhibiting the human serotonin (5-HT) transporter This action leads to increased extracellular serotonin concentrations Fluvoxamine maleate exhibits high binding affinity for the 5-HT transporter with a reported K sub i /sub of 1 6 nmol/l It is widely utilized in biomedical research to investigate serotonergic signaling pathways and to model mechanisms underlying antidepressant activity Fluvoxamine maleate is also available as part of the Serotonin Uptake Inhibitor Tocriset for experimental applications
Medchemexpress LLC 4-(3-aminophenyl)morpholin-3-one | 1082495-22-4 | MFCD11577324 | 50mg
Rivaroxaban impurity 67 is an impurity of Rivaroxaban (HY-50903)